Identification, isolation, purification and modification of Carbohydrate Active Enzymes (CAZymes), especially from (hyper)thermophilic microorganisms, for their exploitation in lignocellulosic biomasses and waste products hydrolysis and valorization Isolation, identification and purification of protein molecules from different natural sources, including cold-adapted proteins from polar organisms. Innovative biocatalysts involved the carbon cycle for CO2 sequestration processes and the production of valuable four-carbon compounds Identification and isolation of enzymes involved in DNA replication, maintenance and repair